Most of our brain cells are glial cells, once thought to be mere support cells, but now understood as having a critical role in brain function. Glial cells in the human brain are markedly different from glial cells in other brains, suggesting that they may be important in the evolution of brain function.
- Thomas R. Insel
Unlike the heart or kidney, which have a small, defined set of cell types, we still do not have a taxonomy of neurons, and neuroscientists still argue whether specific types of neurons are unique to humans. But there is no disputing that neurons are only about 10 percent of the cells in the human brain.
- Thomas R. Insel
Neuroscientists talk a lot about brain circuits. In fact, the word 'circuit' is probably misleading. We do not know where most circuits begin and end. And unlike an electrical circuit, brain connections are heavily reciprocal and recursive, so that a direction of information flow can be inferred but sometimes not proven.
- Thomas R. Insel
Nearly every business collects metrics on inventory, sales, and workplace process. Health care has been slow to measure these kinds of outcomes. Increasingly, general medicine, via either managed care or large practice settings, is improving by collecting data through electronic records and refining practice based on what works.
- Thomas R. Insel
For bipolar in adults, I think there's pretty good agreement about what this looks like. For bipolar in children, there is some considerable debate about where are the boundaries. At the mild end, are these just kids who are active? Is this the class clown at the very severe - is this something other than a mood disorder?
- Thomas R. Insel
What do we know about autism in 2013? Autism symptoms generally emerge before age three and usually much earlier, often as language delays or lack of social engagement. Recent research suggests that autism can be detected during the first year of life, even before classic symptoms emerge. Indeed, the symptoms may be a late stage of autism.
- Thomas R. Insel
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