Jacques Dubochet Quotes

Powerful Jacques Dubochet for Daily Growth

About Jacques Dubochet

Jacques Dubochet (born April 19, 1942) is a Swiss molecular biologist who was awarded the Nobel Prize in Chemistry in 2017 along with Joachim Frank and Richard Henderson for the development of cryo-electron microscopy (Cryo-EM). Born in Orbe, Switzerland, Dubochet grew up in a farming family. His early academic interests were not focused on science, but rather literature and music. However, after attending the University of Lausanne to study physics and chemistry, he found his passion in molecular biology. In 1970, Dubochet joined the laboratory of Arieh Warshel at the Weizmann Institute of Science in Israel. There, he was exposed to cryo-electron microscopy for the first time. This technique allowed scientists to observe biological structures frozen at liquid nitrogen temperatures without the need for staining or sectioning, thereby preserving their native state. Upon returning to Switzerland in 1975, Dubochet joined the Swiss Federal Institute of Technology (ETH Zurich) where he continued his work with Cryo-EM. In 1986, he developed a method for vitrification, a technique that prevents ice crystal formation during freezing and has become an essential step in Cryo-EM sample preparation. Throughout his career, Dubochet has made significant contributions to understanding the structure of biological macromolecules, including viruses, ribosomes, and membrane proteins. His work has played a crucial role in advancing our understanding of cellular processes and diseases at the molecular level. In 2017, Dubochet, along with Frank and Henderson, was awarded the Nobel Prize in Chemistry for their development of Cryo-EM, which has revolutionized structural biology and allowed researchers to study biological structures at near-atomic resolution. Today, Dubochet continues his research at the University of Lausanne as an emeritus professor. Key Quotes: 1. "In science, it often happens that scientists say, 'You know that's been done,' when in fact it has not." - Jacques Dubochet 2. "The future is open and new possibilities are endless." - Jacques Dubochet (at the announcement of his Nobel Prize)

Interpretations of Popular Quotes

"In science, it's important to remember that we're all standing on each other's shoulders."

This quote emphasizes the collaborative nature of scientific discovery. It suggests that progress in science doesn't happen in isolation; instead, scientists build upon the work of those who came before them, much like people standing on each other's shoulders can reach greater heights collectively than individually. In essence, Dubochet is underscoring the importance of collaboration and knowledge-sharing in scientific research, as each discovery serves as a stepping stone for the next generation of researchers to build upon.


"Science is a wonderful adventure: you never know what new discovery awaits around the corner."

This quote by Jacques Dubochet emphasizes the spirit of curiosity, exploration, and excitement inherent in science. It suggests that the pursuit of scientific knowledge is an ongoing journey filled with surprises and discoveries waiting to be made, much like an adventure. The "corner" he refers to symbolizes the unknown or unexpected findings that can arise at any stage in the process of scientific discovery, making each step an opportunity for learning and growth. It underscores the sense of wonder and anticipation that drives scientists to delve deeper into their fields and push the boundaries of human understanding.


"Research is not just about finding answers; it's also about asking the right questions."

This quote emphasizes that research is a process of discovery, but it's not just about finding solutions or facts. It's equally important to identify and formulate the correct questions, as they guide the direction and purpose of the research. The ability to ask insightful questions demonstrates intellectual curiosity, critical thinking, and a deep understanding of the subject matter. By asking the right questions, researchers can uncover new knowledge, challenge existing assumptions, and push the boundaries of human understanding.


"The beauty of science lies in its ability to uncover the hidden mysteries of our world."

This quote by Jacques Dubochet beautifully encapsulates the essence of scientific exploration, emphasizing that it's not just about acquiring knowledge, but also about revealing and understanding the intricate secrets concealed within our world. The "hidden mysteries" could refer to unknown natural phenomena, complex biological processes, or unexplored aspects of the universe – all waiting to be discovered through rigorous scientific inquiry. This quest for understanding, sparked by curiosity, fuels human progress and brings us closer to a more comprehensive understanding of our world.


"To me, the most exciting aspect of science is that it's a journey without end - there will always be new questions to explore and answer."

This quote by Jacques Dubochet underscores the infinite nature and perpetual curiosity at the heart of scientific exploration. By suggesting that science is a boundless journey, he highlights its inherent appeal: the constant discovery of fresh mysteries to solve and questions to address. This mindset not only fosters innovation but also fuels human's insatiable quest for understanding our world, fueling advancements across various fields.


In our group, it was a necessary requirement that one has to be able to collaborate.

- Jacques Dubochet

Necessary, Able, Requirement, Collaborate

We three have never been very good chemists but we are gratified with a Nobel Prize in Chemistry. The Peter Principle says that everyone is promoted until they reach their level of incompetence. We are worried that we may have reached this remarkable point.

- Jacques Dubochet

Been, Principle, Very, Nobel Prize

A scientific prize is an ambiguous thing: it highlights an individual when we should highlight a collective effort, but I'm not alone.

- Jacques Dubochet

Individual, Scientific, Highlights

It would be great if you could cool the water and immobilise the molecules, though keeping the structure, because when it's frozen, when it's immobilised, you can have it in the electron microscope and the water will not evaporate because in the electron microscope, it must be under vacuum, and water at normal temperature evaporates.

- Jacques Dubochet

Molecules, Evaporates, Would, Electron

Rather big part of my time is to read scientific journals and to discover what others are doing.

- Jacques Dubochet

Discover, Big, Big Part, Journals

I hate personal competition, and so each time in my career I came in a field where it was highly competitive, I gave up.

- Jacques Dubochet

Career, Personal, Each Time, Highly

We see chemistry, how the atoms are arranged in the molecules, how the disease changes the arrangement. Perhaps we will find which drug disentangles the aggregates that make a brain senile. Many of us are interested in such things.

- Jacques Dubochet

Changes, Molecules, Atoms, Senile

The world is large, very large. My head is small, quite small. There is no way I can put the world in my head. Nevertheless, I have been trying to elaborate some kind of representation.

- Jacques Dubochet

Small, Very, Elaborate, Representation

Chemistry is the science of atoms. Elaborating on Democritus' idea, chemists learn how atoms stick or don't stick together, thus forming molecules.

- Jacques Dubochet

Chemistry, Forming, Thus, Molecules

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