One can, in principle, outline sort of a set of neural circuits that are critically involved and even identify disorders that affect different components of that neural circuit and see what happens if you knock out, for example, inability to recognize faces, how it affects your response to portraiture.
- Eric Kandel
I had many moments of disappointment, despondency, and exhaustion, but I always found that by reading the literature and showing up at my lab looking at the data as they emerged day by day and discussing them with my students and postdoctoral fellows, I would gain a notion of what to do next.
- Eric Kandel
It may act as an ancillary factor, but by itself, the mutation in tau doesn't give you Alzheimer's disease. This is not to say the tau is not very important. It may be important in propagating the disorder from one cell to another. But as a causal mechanism, the evidence is strongest for beta amyloid abnormalities.
- Eric Kandel
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