David Perlmutter Quotes

A fundamental premise in cancer therapy is trying to identify how the metabolism of cancer cells differs from normal tissue. When differences are identified, it often paves the way for treatments that will disrupt the cancer's metabolism while sparing normal tissue.

- David Perlmutter

Bad things happen. And the human brain is especially adept at making sure that we keep track of these events. This is an adaptive mechanism important for survival.

- David Perlmutter

While the hippocampus itself doesn't store memories, it serves to triage our experiences based upon their survival significance.

- David Perlmutter

Saturated fat is a fundamental building block for brain cells. It's certainly interesting to consider that one of the richest sources of saturated fat in nature is human breast milk.

- David Perlmutter

Two forms of fat that are vitally important for brain health are cholesterol and saturated fat.

- David Perlmutter

Alzheimer's is a disease for which there is no effective treatment whatsoever. To be clear, there is no pharmaceutical agent, no magic pill that a doctor can prescribe that will have any significant effect on the progressive downhill course of this disease.

- David Perlmutter

Parkinson's is described as a progressive idiopathic neurodegenerative disorder, a brain disease that will worsen with time for which no cause has as yet been identified.

- David Perlmutter

Increase your consumption of healthful fats like extra virgin olive oil, avocado, grass-fed beef, wild fish, coconut oil, nuts and seeds. At the same time, keep in mind that modified fats like hydrogenated or trans fats are the worst choices for brain health.

- David Perlmutter

Far from being entirely dependent on exogenous food sources of antioxidants, our cells have their own innate ability to generate antioxidants upon demand.

- David Perlmutter

Food is medicine. We can actually change our gene expressions with the foods we eat.

- David Perlmutter

Strokes are categorized as either bleeding into the brain or a blockage in blood supply, known as an ischemic stroke. The latter are overwhelmingly more common, compromising about 87 percent of all stroke events.

- David Perlmutter

When a child is watching television, he or she is not involved in play, not socializing with other individuals, and most importantly, not receiving feedback as to the actions or consequences of his or her behavior.

- David Perlmutter

So-called 'complex carbs' may actually represent a more significant threat to health than simple sugar in that they may not only raise blood sugar, but keep it elevated for a more prolonged period of time.

- David Perlmutter

Rarely, Type 2 diabetes develops without any readily identifiable predisposing factor. But in the great majority of cases, it is brought on by lifestyle activities, including, and clearly most importantly, dietary choices.

- David Perlmutter

Memory enhancement self-help programs abound and promise improved memory performance by the utilization of any number of seemingly unique techniques focused on the context of how information is encoded.

- David Perlmutter

The human brain is at particularly high risk for damage by free radicals because of its high degree of metabolism compared to other tissues, while lacking the levels of antioxidant protection found elsewhere in the body.

- David Perlmutter

Our ancestors relied upon their advanced brains to survive during times of food shortage, and fortunately, the human brain is able to utilize body fat as an extremely efficient fuel to sustain function when glucose-providing food is unavailable.

- David Perlmutter

The science supporting the relationship between carbohydrates and dementia is quite exciting, as it paves the way for lifestyle changes that can profoundly affect a person's chances of remaining intact, at least from a brain perspective.

- David Perlmutter

In general, the public knowledge base and thus decision-making behaviors are far more influenced by advertisement than with current science.

- David Perlmutter

The best diet for overall health, and specifically for heart, brain, and cancer risk reduction, is a diet that's aggressively low in carbohydrates with an abundance of healthful fat, and this is the central theme of 'Grain Brain.'

- David Perlmutter

Most grain foods, whether we're talking about quinoa, amaranth, the very popular grains of the day - the reality is they still are associated with a carbohydrate surge.

- David Perlmutter

The idea that people are nutritionally deprived because they don't eat grain has no scientific basis.

- David Perlmutter

This low-fat idea that's been drummed into our heads and bellies is completely off-base and deeply responsible for most of our modern ills.

- David Perlmutter

The Mediterranean diet is rich in fruits and vegetables while low in sodium. It is also enriched with olive oil, high in antioxidants as well as monounsaturated and polyunsaturated fats.

- David Perlmutter

Throughout our lifetimes, we are constantly regenerating new brain cells in the hippocampus, a process called neurogenesis. New stem cells are constantly being born in the hippocampus that ultimately differentiate into fully functional neurons.

- David Perlmutter

Fat is your friend. The brain thrives on a fat-rich, low-carbohydrate diet.

- David Perlmutter

When we are exposed to a real or perceived threatening situation, powerful things happen in the brain to memorialize aspects of the event, including all manner of associated circumstances like where, when and how it occurred.

- David Perlmutter

It may seem draconian, but the best recommendation I can make is to completely avoid grains.

- David Perlmutter

Inflammation is the cornerstone of Alzheimer's disease and Parkinson's, multiple sclerosis - all of the neurodegenerative diseases are really predicated on inflammation.

- David Perlmutter

As a practicing neurologist, I can tell you first hand that working with Parkinson's patients offers clinical challenges. But from an emotional perspective, this disease can border on overwhelming.

- David Perlmutter

Dementia is our most-feared illness, more than heart disease or cancer.

- David Perlmutter

As a practicing neurologist, I place central importance in applying current science to the notion of disease prevention.

- David Perlmutter

Antioxidants are chemicals that break down or neutralize the damaging effects of free radicals - chemicals produced as a byproduct of normal cellular metabolism.

- David Perlmutter

From the earliest moments of life, children begin to learn the fundamentals of language. The most powerful influence for effective language development are the verbal interactions with caregivers.

- David Perlmutter

Even slight elevations in blood sugar have been shown to increase the risk of Alzheimer's disease.

- David Perlmutter

The story of gluten as it relates to the brain throws a wide net, so much more encompassing than the inflammation of a small section of the small intestine that characterizes celiac disease.

- David Perlmutter

Shoot for a total of no more than 80 grams of carbs in your daily diet. This means favoring vegetables that grow above ground like kale, broccoli, spinach, and cauliflower as opposed to those that store carbohydrate in the form of starch like potatoes and beets.

- David Perlmutter

Children need to be exploring their physical world. They need to be learning the fundamental laws of physics by manipulating objects.

- David Perlmutter

The bottom line is that this author, a practicing neurologist dealing with Alzheimer's disease on a daily basis, believes we need to expand the public awareness that modifiable lifestyle factors have a profound role to play in determining who will or won't get this disease.

- David Perlmutter

People are getting to this place of understanding that their lifestyle choices actually do matter a whole lot as opposed to this notion that you live your life, come what may, and hope for a pill.

- David Perlmutter

The food we eat goes beyond its macronutrients of carbohydrates, fat and protein. It's information. It interacts with and instructs our genome with every mouthful, changing genetic expression.

- David Perlmutter

Humans are not the fastest or the strongest animals on the planet, but when it comes to survival, we have had the unique advantage of being clever.

- David Perlmutter

The biggest issue by far is that carbohydrates are absolutely at the cornerstone of all of our major degenerative conditions.

- David Perlmutter

Carbohydrates, whether derived from gluten-containing foods or other sources, including fruit, sweetened beverages, and starchy vegetables, are dangerous as they relate to brain health in and of themselves.

- David Perlmutter

Carbs are devastating for the brain.

- David Perlmutter

Making changes in the fast food that makes up such a significant part of the American diet, even if the numbers aren't impressive, will have important health up sides.

- David Perlmutter

Mental fitness is served by consciously redirecting our attention away from the constant bombardment from the media whose reason to be seems to be focused on keeping us in a state of constant alert.

- David Perlmutter